THE KORNGREEN LAB Cellular and Computational Neurophysiology
Publications

EDITED BOOKS

  1. Korngreen, A. (2016) Advanced Patch-Clamp Analysis for Neuroscientists. Humana Press.

JOURNAL ARTICLES

  1. Korngreen, A. and Priel, Z. (1994) Simultaneous measurement of intracellular calcium and ciliary beating. Biophys. J. 67, 377-380.
  2. Tarasiuk, A., Bar-Shimon, M., Gheber, L., Korngreen, A., Grossman, Y. and Priel, Z. (1995) Extracellular ATP induces hyperpolarization and motility stimulation of ciliary cells. Biophys. J. 68, 1163-1169.
  3. Alfahel, E., Korngreen, A., Parola, A.H. and Priel, Z. (1996) Purinergically induced membrane fluidization in ciliary cells: characterization and control by calcium and membrane potential. Biophys. J. 70, 1045-1053.
  4. Korngreen, A. and Priel, Z. (1996) Purinergic stimulation of rabbit ciliated airway epithelia: control by multiple calcium sources. J. Physiol. (Lond.) 497, 53-66.
  5. Korngreen, A., Gold’shtein, V. and Priel, Z. (1997) Realistic modeling of biphasic calcium transients in electrically nonexcitable cells. Biophys. J. 73, 659-673.
  6. Gheber, L., Korngreen, A. and Priel, Z. (1998) Effect of viscosity on metachrony in mucus propelling cilia. Cell Motil. Cytoskeleton 39, 9-20.
  7. Korngreen, A. and Priel, Z. (1998) Mucus transporting cilia: A model system for investigating calcium signaling in electrically inexcitable cells. In: Cilia, Mucus, and Mucociliary Interactions. Marcel Dekker, NY, pp. 49-58.
  8. Korngreen, A., Ma, W., Priel, Z. and Silberberg, S.D. (1998) Extracellular ATP directly gates a cation-selective channel in rabbit airway ciliated epithelial cells. J. Physiol. (Lond.) 508, 703-720.
  9. Weiyuan, M., Korngreen, A., Uzlaner, N., Priel, Z. and Silberberg, S.D. (1999) Extracellular Na+ regulates airway ciliary motility by inhibiting a P2X receptor. Nature 400, 894-897.
  10. Korngreen, A. and Sakmann, B. (2000) Voltage gated K+ channels in layer 5 neocortical pyramidal neurones from young rats: subtypes and gradients. J. Physiol. 525, 621-639.
  11. Silberberg, S.D., Korngreen, A., Ma, W., Uzlaner, N. and Priel, Z. (2001) Modulation of ciliary motility by Na+ In: Cilia and Mucus: From Development to respiratory defense. Marcel Dekker, NY, pp. 81-90.
  12. Gensler, S., Sander, A., Korngreen, A., Traina, G., Giese, G. and Witzemann, V. (2001). Acetylcholine receptor- and -subunits tagged with green fluorescent protein are incorporated at the neuromuscular junction in vivo. Eur. J. Biochem. 268, 2209-2217.
  13. Schaefer, A.T., Helmstaedter, M., Sakmann, B. and Korngreen, A. (2003) Correction of conductance measurements in non-space-clamped structures: 1. Voltage-gated K+ channels. Biophys. J. 84, 3508-3528.
  14. Korngreen, A., Kaiser, KMM., Zilberter Y. (2005) Subthreshold Inactivation of Voltage-gated K+ Channels Modulates Action Potentials in Neocortical Bitufted Interneurones J. Physiol. 562, 421-437.
  15. Peter, C., Korngreen, A. and Witzemann, V. (2005). Mutation of single murine acetylcholine receptor subunits reveals differential contribution of P121 to acetylcholine binding and to channel opening. Pflug. Arch. Eur. J. Physiol. 450, 178–184.
  16. Keren, N. Peled, N. and Korngreen A. (2005). Constraining compartmental models using multiple voltage-recordings and genetic algorithms. J. Neurophysiol. 94: 3730-3743
  17. Ma, W., Korngreen, A., Weil, S., Ben-Tal Cohen, E., Priel, A., Kuzin, L., Silberberg, SD. (2006). Pore properties and pharmacological features of the P2X receptor channel in airway ciliated cells. J. Physiol. 571: 503-517.
  18. Gurkiewicz, M., Korngreen, A. (2006) Recording, Analysis and Function of Dendritic Voltage-Gated Channels. Pflug. Arch. Eur. J. Physiol. 453: 283-292
  19. Schaefer, AT., Helmstaedter, M., Schmitt, AC., Bar-Yehuda, D., Almog, M., Ben-Porat, H., Sakmann, B. and Korngreen, A (2007) Dendritic voltage-gated K+ conductance gradient in neocortical pyramidal neurones. J. Physiol. 579: 737-752
  20. Michaelevski, I., Korngreen A., and Lotan, I. (2007) Interaction of syntaxin 1A with a presynaptic voltage-gated K+ channel: a possible mechanism for modulation of synaptic integration. Pflug. Arch. Eur. J. Physiol. 454:477-494
  21. Gurkiewicz, M., and Korngreen, A. (2007). A numerical approach to ion channel modelling using whole-cell voltage-clamp recordings and a genetic algorithm. PLoS Comp Biol 3(8): e169.
  22. Segev D., and Korngreen, A. (2007). Kinetics of two voltage-gated K+ conductances in substantia nigra dopaminergic neurons. Brain Res 1173: 27-35.
  23. Bar-Yehuda, D., and Korngreen, A. (2007). Cellular and network contributions to excitability of layer 5 neocortical pyramidal neurons in the rat PLoS ONE 2(11): e1209
  24. Hurwitz, I., Ophir, A., Korngreen, A., Koester, J., and Susswein AJ. (2008) Currents Contributing to Decision-Making in Neurons B31/B32 of Aplysia. J. Neurophysiol. 99: 814–830.
  25. Bar-Yehuda, D., and Korngreen, A. (2008). Space clamp problems when voltage clamping neurons expressing voltage-gated conductances. J. Neurophysiol 99: 1127–1136.
  26. Pomp O, Brokhman I, Ziegler L, Almog M, Korngreen A, Tavian M, Goldstein RS. (2008) PA6-induced human embryonic stem cell-derived neurospheres: a new source of human peripheral sensory neurons and neural crest cells. Brain Res. 1230:50-60.
  27. Bar-Yehuda D., Hana Ben-Porat, H., and Korngreen A. (2008) Dendritic excitability during increased synaptic activity in rat neocortical L5 pyramidal neurons European Journal of Neuroscience, 28, 2183–2194.
  28. Keren, N., Bar-Yehuda, D., and Korngreen, A. (2009) Experimentally guided modeling of dendritic excitability in rat neocortical pyramidal neurons. J. Physiol. 587: 1413-1437.
  29. Almog, M. and Korngreen, A. (2009) Characterization of voltage-gated Ca2+ channels in layer 5 neocortical pyramidal neurons from rats PLoS ONE, 4:e4841.
  30. Regev N, Degani-Katzav N, Korngreen A, Etzioni A, Siloni S, Alaimo A, Chikvashvili D, Villarroel A, Attali B, Lotan I, (2009) Selective Interaction of Syntaxin 1A with KCNQ2: Possible Implications for Specific Modulation of Presynaptic Activity. PLoS ONE 4(8): e6586.
  31. Bronfeld M, Belelovsky K, Erez Y, Bugaysen J, Korngreen A, Bar-Gad I. (2010) Bicuculline induced chorea manifests in focal rather than globalized abnormalities in the activation of the external and internal globus pallidus. J Neurophysiol. 104(6):3261-75.
  32. Bugaysen J, Bronfeld M, Tischler H, Bar-Gad I, Korngreen A. (2010) Electrophysiological characteristics of globus pallidus neurons. PLoS One 5(8): e12001.
  33. Tischler, H., Wolfus, S., Friedman, A., Perel, E., Pashut, T., Lavidor, M., Korngreen A., Yeshurun, Y, Bar-Gad, I. (2011) Mini-coil for magnetic stimulation in the behaving primate, J. Neurosci Methods. 15; 194(2): 242-51.
  34. Gurkiewicz M, Korngreen A, Waxman SG, Lampert A. (2011). Kinetic Modeling of Nav1.7 Provides Insight Into Erythromelalgia-associated F1449V Mutation. Journal of Neurophysioloy 105(4): 1546-57.
  35. Pashut, T., Wolfus, S. Friedman, A., Lavidor, M. Bar-Gad, I. Yeshurun, Y., and Korngreen A. (2011) Mechanisms of magnetic stimulation of central nervous system neurons. PLoS Computational Biology 7(3): e1002022
  36. Bugaysen J, Bar-Gad I and Korngreen A (2011). The impact of stimulation induced short-term synaptic plasticity on firing patterns in the globus pallidus of the rat. Frontiers in Systems Neuroscience 5:16.
  37. Berger, U., Korngreen, A., Bar-Gad, I., Friedman A., Wolfus, S., Yeshurun, Y., and Lavidor M. (2011) Magnetic stimulation intensity modulates motor inhibition. Neuroscience Letters. 504(2): 93-7.
  38. Ben-Shalom R, Aviv A Razon, B. and Korngreen A. (2012) Optimizing ion channel kinetics using a massively parallel genetic algorithm on a graphical processing unit. Journal of Neuroscience Methods. 15;206(2):183-94
  39. Tischler, H. Moran A, Belelovsky K, Bronfeld M, Korngreen A, Bar-Gad I. (2012) Changes in basal ganglia processing of cortical input following magnetic stimulation in Parkinsonism Neurobiology of disease 48, 464-473
  40. Ben-Shalom R, Liberman G, Korngreen A. (2013) Accelerating compartmental modeling on a graphical processing unit. Front Neuroinform.18;7:4.
  41. Bugaysen J, Bar-Gad I, Korngreen A. (2013) Continuous modulation of action potential firing by a unitary GABAergic connection in the globus pallidus in vitro. J Neurosci. 31;33(31):12805-9
  42. M Brody, and Korngreen. A. (2013) Simulating the effects of short-term synaptic plasticity on postsynaptic dynamics in the globus pallidus Front. Syst. Neurosci., 08 August 2013 7:40,1-11 | doi: 10.3389/fnsys.2013.00040
  43. Lavian H, Ben Porat H and Korngreen A (2013) High and low frequency stimulation of the subthalamic nucleus induce prolonged changes in subthalamic and globus pallidus neurons. Front. Syst. Neurosci. 7:73,1-8. doi: 10.3389/fnsys.2013.00073
  44. Tzachi Sabati; Bat-Sheva Galmidi; Alon Korngreen; Naomi Zurgil; Mordechai Deutsch J.Real-time monitoring of changes in plasma membrane potential via imaging of fluorescence resonance energy transfer at individual cell resolution in suspension Biomed. Opt. 18 (12), 126010 (December 16, 2013); 18. 126010-20
  45. Almog M, Korngreen A. (2014) A quantitative description of dendritic conductances and its application to dendritic excitation in layer 5 pyramidal neurons. J Neurosci. 2014 Jan 1;34(1):182-96.
  46. Pashut T, Magidov D, Ben-Porat H, Wolfus S, Friedman A, Perel E, Lavidor, M, Bar-Gad I, Yeshurun Y and Korngreen A (2014) Patch-clamp recordings of rat neurons from acute brain slices of the somatosensory cortex during magnetic stimulation. Front. Cell. Neurosci. 8:145. 1-12 doi: 10.3389/fncel.2014.0014
  47. Lavian H, Korngreen A. (2015). Inhibitory short-term plasticity modulates neuronal activity in the rat entopeduncular nucleus in vitro. Eur J Neurosci. 2015 May 25. doi: 10.1111/ejn.12965.
  48. Almog M, Korngreen A. (2016) Is realistic neuronal modeling realistic? J Neurophysiol. 116(5):2180-2209
  49. Korngreen A.(2017) Visualizing fundamental neuronal computation for life science students. Adv Physiol Educ.41(2):312-314
  50. Lavian H, Almog M, Madar R, Loewenstern Y, Bar-Gad I, Okun E, Korngreen A. (2017) Dopaminergic Modulation of Synaptic Integration and Firing Patterns in the Rat Entopeduncular Nucleus. J Neurosci.37(30):7177-7187
  51. M Almog, T Barkai, A Lampert, A Korngreen (2018) Voltage-gated sodium channels in neocortical pyramidal neurons display Cole-Moore activation kinetics Frontiers in Cellular Neuroscience 12, 187
  52. H Lavian, Y Loewenstern, R Madar, M Almog, I Bar-Gad, E Okun, A Korngreen (2018) Dopamine receptors in the rat entopeduncular nucleus Brain Structure and Function 223 (6), 2673-2684
  53. Mark Grobman, Tal Dalal, Hagar Lavian, Ronit Shmuel, Katya Belelovsky, Fuqiang Xu, Alon Korngreen, Rafi Haddad (2018) A mirror-symmetric excitatory link coordinates odor maps across olfactory bulbs and enables odor perceptual unity. Neuron 99 (4), 800-813
  54. L Gorodetski, R Zeira, H Lavian, A Korngreen (2018) Long‐term plasticity of glutamatergic input from the subthalamic nucleus to the entopeduncular nucleus European Journal of Neuroscience 48 (5), 2139-2151
  55. A Faynveitz, H Lavian, A Jacob, A Korngreen (2019) Proliferation of inhibitory input to the Substantia Nigra in Experimental Parkinsonism Frontiers in cellular neuroscience 13, 417
  56. H Lavian, A Korngreen (2019) Short-term depression shapes information transmission in a constitutively active GABAergic synapse Scientific reports 9 (1), 1-15
  57. A Matzner, L Gorodetski, A Korngreen, I Bar-Gad (2020) Dynamic input-dependent encoding of individual basal ganglia neurons Scientific reports 10 (1), 1-13
  58. R Schick, N Farah, A Markus, A Korngreen, Y Mandel (2021) Electrophysiologic characterization of developing human embryonic stem cell-derived photoreceptor precursors. Investigative Ophthalmology & Visual Science 61 (11), 44-44.
  59. R Ben-Shalom, A Ladd, NS Artherya, C Cross, KG Kim, H Sanghevi, et al. (2022) NeuroGPU: Accelerating multi-compartment, biophysically detailed neuron simulations on GPUs. Journal of neuroscience methods 366, 109400.
  60. M Almog, N Degani-Katzav, A Korngreen (2022) Kinetic and thermodynamic modeling of a voltage-gated sodium channel. European Biophysics Journal 51 (3), 241-256.
  61. NG Glasgow, Y Chen, A Korngreen, RE Kass, NN Urban (2023) A biophysical and statistical modeling paradigm for connecting neural physiology and function. Journal of Computational Neuroscience 51 (2), 263-282.
  62. S Kriegeskorte, R Bott, M Hampl, A Korngreen, R Hausmann, A Lampert (2023) Cold and warmth intensify pain-linked sodium channel gating effects and persistent currents. Journal of General Physiology 155 (9), e202213312.
  63. A Korngreen (2025) Sensitivity analysis of voltage-gated ion channel models. bioRxiv, 2025.08.05.668838.
  64. A Korngreen (2026) Neuronal excitability and parameter variability in the Hodgkin-Huxley model. bioRxiv, 2025.12.30.696982.

BOOKS CHAPTERS

  1. Angelika Lampert, and Alon Korngreen, Markov Modeling of Ion Channels: Implications for Understanding Disease. In Kim T. Blackwell, editor: Progress in Molecular Biology and Translational Science, Vol. 123, Burlington: Academic Press, 2014, pp. 1-21
  2. A Korngreen, T Nevian, J Schiller. Patching Dendrites. In The Handbook of Electrophysiology: A Practical Guide for Neurophysiologists.

SCIENTIFIC CORRESPONDENCE

  1. Korngreen, A. (2004) Noise in the foreground. J. Neurophysiol. 94, 2400.
  2. Korngreen, A. (2005). Peer-review system could gain from author feedback. Nature, 438 :282
  3. Bourne PE., Korngreen, A. (2006) Ten simple rules for reviewers, PLoS Comp Biol 2:973-974
  4. Gurkiewicz M, Korngreen A. (2009). Too much quantification hinders creativity. Science 323:1662-4.
  5. Gurkiewicz M, Iron D, Bar‐Gad I & Korngreen A (2009) Rise of The Appendage. Front. Neuroinform.doi:10.3389/neuro.11.032.2009
  6. Schiller J., Korngreen A., Polsky A., de Kock C.P.J. (2009) The multifaceted physiology of action potentials in neocortical pyramidal neurons. CellSciRev 6(2): 6 - 18.
  7. Ahmed A. Moustafa, Izhar Bar-Gad, Alon Korngreen and Hagai Bergman. (2014). Basal ganglia: physiological, behavioral, and computational studies. Front. Syst. Neurosci., | doi: 10.3389/fnsys.2014.00150, 1-4

EDITORIAL COMMENTARIES ABOUT MY PAPERS

  1. Storm JF. (2000) K+ channels and their distribution in large cortical pyramidal neurons. J. Physiol. 525, 565-566
  2. Häusser M. (2003) Revealing the Properties of Dendritic Voltage-Gated Channels: A New Approach to the Space Clamp Problem. Biophys. J. 84, 3497–3498
  3. Roth, A. and Bahl, A. (2009) Divide et impera: optimizing compartmental models of neurons step by step. J. Physiol. 587, 1369-1370.